ST6GALNAC4 antibody (AA 39-302)

Catalog No. ABIN7874595

The Rabbit Polyclonal anti-ST6GALNAC4 antibody is suitable to detect ST6GALNAC4 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for ST6GALNAC4 antibody (AA 39-302) (ABIN7874595)

Target: ST6GALNAC4 (ST6 (Alpha-N-Acetyl-Neuraminyl-2,3-beta-Galactosyl-1,3)-N-Acetylgalactosaminide alpha-2,6-Sialyltransferase 4 (ST6GALNAC4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ST6GALNAC4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ST6GALNAC4 Antibody

Binding Specificity: AA 39-302

Purpose: ST6GALNAC4 Antibody

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids D39-T302) was used as the immunogen for the ST6GALNAC4 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ST6GALNAC4 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ST6GALNAC4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ST6GALNAC4

Target: ST6GALNAC4 (ST6 (Alpha-N-Acetyl-Neuraminyl-2,3-beta-Galactosyl-1,3)-N-Acetylgalactosaminide alpha-2,6-Sialyltransferase 4 (ST6GALNAC4))

Alternative Name: ST6GALNAC4

Background: ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4, also known as sialyltransferase 3C (SIAT3-C) or sialyltransferase 7D (SIAT7-D) is a sialyltransferase enzyme that in humans is encoded by the ST6GALNAC4 gene. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein prefers glycoproteins rather than glycolipids as substrates and shows restricted substrate specificity, utilizing only the trisaccharide sequence Neu5Ac-alpha-2,3-Gal-beta-1,3-GalNAc. In addition, it is involved in the synthesis of ganglioside GD1A from GM1B. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Transcript variants encoding different isoforms have been found for this gene. Readthrough transcripts exist for this gene and the downstream ST6GALNAC6 gene.

UniProt: Q9H4F1