FLNB antibody (AA 397-701)

Catalog No. ABIN7874650

The Mouse Monoclonal anti-FLNB antibody (Clone 11E2D2) (ABIN7874650) specifically detects FLNB in WB, IF and IHC (p). The antibody is reactive with Human samples.

Quick Overview for FLNB antibody (AA 397-701) (ABIN7874650)

Target: FLNB (Filamin B, beta (FLNB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FLNB antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 11E2D2

Product Details anti-FLNB Antibody

Binding Specificity: AA 397-701

Purpose: Filamin B Antibody / Migfilin-1 / FLNB / FBLIM1

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids Q397-D701) was used as the immunogen for the Filamin B antibody.

Isotype: IgG1

Application Details

Application Notes: Optimal dilution of the Filamin B antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Filamin B antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for FLNB

Target: FLNB (Filamin B, beta (FLNB))

Alternative Name: Filamin B

Background: Filamin B, beta (FLNB), also known as Filamin B (truncated actin binding protein 278 homolog), is a cytoplasmic protein which in humans is encoded by the FLNB gene. This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3, boomerang dysplasia, autosomal dominant Larsen syndrome, and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

UniProt: O75369

Pathways: Maintenance of Protein Location