LAGE3 antibody (AA 40-143)

Catalog No. ABIN7874689

The Rabbit Polyclonal anti-LAGE3 antibody (ABIN7874689) specifically detects LAGE3 in WB, ELISA and IF. The antibody is reactive with Human samples.

Quick Overview for LAGE3 antibody (AA 40-143) (ABIN7874689)

Target: LAGE3 (L Antigen Family, Member 3 (LAGE3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LAGE3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-LAGE3 Antibody

Binding Specificity: AA 40-143

Purpose: ESO-3 Antibody / LAGE3 / ITBA2

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (amino acids A40-R143) was used as the immunogen for the ESO-3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ESO-3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ESO-3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for LAGE3

Target: LAGE3 (L Antigen Family, Member 3 (LAGE3))

Alternative Name: ESO-3

Background: This gene belongs to the ESO/LAGE gene family, members of which are clustered together on chromosome Xq28, and have similar exon-intron structures. Unlike the other family members which are normally expressed only in testis and activated in a wide range of human tumors, this gene is ubiquitously expressed in somatic tissues. The latter, combined with the finding that it is highly conserved in mouse and rat, suggests that the encoded protein is functionally important. An intronless pseudogene with high sequence similarity to this gene is located on chromosome 9.

UniProt: Q14657