Neurogenin 3 antibody (AA 40-69)

Catalog No. ABIN7874708

This Rabbit Polyclonal antibody specifically detects Neurogenin 3 in WB, IF and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for Neurogenin 3 antibody (AA 40-69) (ABIN7874708)

Target: Neurogenin 3 (NEUROG3)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neurogenin 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Neurogenin 3 Antibody

Binding Specificity: AA 40-69

Purpose: NGN3 Antibody / Neurogenin 3

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 40-69 from the human protein were used as the immunogen for the NGN3 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the NGN3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the NGN3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Neurogenin 3

Target: Neurogenin 3 (NEUROG3)

Alternative Name: NGN3

Background: Neurogenin-3 belongs to a family of basic helix-loop-helix transcription factors involved in the determination of neural precursor cells in the neuroectoderm. Neurogenin-3 also required for the specification of a common precursor of the 4 pancreatic endocrine cell types. Defects in NEUROG3 are the cause of congenital malabsorptive diarrhea 4 (DIAR4). DIAR4 is an autosomal recessive disorder characterized by generalized malabsorption and a paucity of enteroendocrine cells.

UniProt: Q9Y4Z2