Syncytin A (SYNA) (AA 400-429) antibody

Catalog No. ABIN7874713

The Rabbit Polyclonal anti-Syncytin A antibody (ABIN7874713) specifically detects Syncytin A in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Syncytin A (SYNA) (AA 400-429) antibody (ABIN7874713)

Target: Syncytin A (SYNA)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details

Binding Specificity: AA 400-429

Purpose: Syncytin 1 Antibody / ERVW-1

Immunogen: A portion of amino acids 400-429 from the human protein was used as the immunogen for this Syncytin 1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Syncytin 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Syncytin 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details

Target: Syncytin A (SYNA)

Alternative Name: Syncytin 1

Background: Syncytin 1 is a protein encoded by the ERVW-1 gene, which belongs to the human endogenous retrovirus W family. Endogenous retroviruses are remnants of ancient viral infections that have inserted their genetic material into the human genome. These genetic elements have been preserved through generations and have been co-opted by our bodies for various functions. One of the most intriguing functions of Syncytin 1 is its role in placental development. During pregnancy, Syncytin 1 is expressed in the trophoblast cells of the placenta, where it helps in the formation of syncytia - multinucleated cells that facilitate nutrient exchange between the mother and the growing fetus. This process is essential for the successful progression of pregnancy and the health of both the mother and the baby. Recent research has pointed to its involvement in various physiological processes, including immune modulation and tissue repair. Its expression has been detected in the brain, where it may play a role in neuroprotection and synaptic plasticity.

UniProt: Q9UQF0