Glucuronidase beta antibody (AA 416-651)

Catalog No. ABIN7874907

The Rabbit Polyclonal anti-Glucuronidase beta antibody is suitable to detect Glucuronidase beta in samples from Human. It has been validated for WB, ELISA, ICC, IF, FACS and IHC (p).

Quick Overview for Glucuronidase beta antibody (AA 416-651) (ABIN7874907)

Target: Glucuronidase beta (GUSB) (Glucuronidase, beta (GUSB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glucuronidase beta antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Glucuronidase beta Antibody

Binding Specificity: AA 416-651

Purpose: Beta Glucuronidase Antibody / Gusb

Purification: Affinity purified

Immunogen: A human recombinant protein (amino acids Q416-T651) was used as the immunogen for the Beta Glucuronidase antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Beta Glucuronidase antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Beta Glucuronidase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Glucuronidase beta

Target: Glucuronidase beta (GUSB) (Glucuronidase, beta (GUSB))

Alternative Name: Beta Glucuronidase

Background: Beta-glucuronidases are members of the glycosidase family of enzymes that catalyze breakdown of complex carbohydrates. This gene encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin-4,6-sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. Alternative splicing results in multiple transcript variants. There are many pseudogenes of this locus in the human genome.

UniProt: P08236

Pathways: Glycosaminoglycan Metabolic Process