SH2D4A antibody (AA 42-454)

Catalog No. ABIN7874923

The Rabbit Polyclonal anti-SH2D4A antibody (ABIN7874923) specifically detects SH2D4A in WB, ELISA, FACS, IHC (p) and IF. The antibody is reactive with Human and Rat samples.

Quick Overview for SH2D4A antibody (AA 42-454) (ABIN7874923)

Target: SH2D4A (SH2 Domain Containing 4A (SH2D4A))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH2D4A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-SH2D4A Antibody

Binding Specificity: AA 42-454

Purpose: SH2D4A Antibody / PPP1R38

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids R42-E454) was used as the immunogen for the SH2D4A antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the SH2D4A antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the SH2D4A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SH2D4A

Target: SH2D4A (SH2 Domain Containing 4A (SH2D4A))

Alternative Name: SH2D4A

Background: SH2 domain-containing protein 4A, also called Protein phosphatase 1 regulatory subunit 38 (PPP1R38) is a protein that in humans is encoded by the SH2D4A gene. Using exon trapping and exon linking at chromosome 8p22 cloned SH2D4A, which they called SH2A. The deduced 454-amino acid protein contains a single SH2 domain. RT-PCR and Northern blot analysis detected ubiquitous expression of 3 SH2A transcripts, as well as aberrant expression in some cancer cell lines. Dai et al. (2002) concluded that SH2A is a docking protein that may be involved in signal transduction.

UniProt: Q9H788