Nucleostemin antibody (AA 420-454)

Catalog No. ABIN7874932

The Rabbit Polyclonal anti-Nucleostemin antibody (ABIN7874932) specifically detects Nucleostemin in WB. The antibody is reactive with Human and Mouse samples.

Quick Overview for Nucleostemin antibody (AA 420-454) (ABIN7874932)

Target: Nucleostemin (GNL3) (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (GNL3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nucleostemin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Nucleostemin Antibody

Binding Specificity: AA 420-454

Purpose: Gnl3 Antibody

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 420-454 from the mouse protein was used as the immunogen for the Gnl3 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Gnl3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Gnl3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Nucleostemin

Target: Nucleostemin (GNL3) (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (GNL3))

Alternative Name: Gnl3

Background: Guanine nucleotide-binding protein-like 3 may be required to maintain the proliferative capacity of stem cells (By similarity). Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation. [UniProt]

UniProt: Q8CI11