IGF2R antibody (AA 424-529)

Catalog No. ABIN7874935

The Mouse Monoclonal anti-IGF2R antibody (Clone 4I11) (ABIN7874935) specifically detects IGF2R in WB, FACS, IF and IHC (p). The antibody is reactive with Human samples.

Quick Overview for IGF2R antibody (AA 424-529) (ABIN7874935)

Target: IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IGF2R antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 4I11

Product Details anti-IGF2R Antibody

Binding Specificity: AA 424-529

Purpose: IGF2R Antibody / M6PR

Purification: Affinity purified

Immunogen: An E. coli-derived human protein (amino acids F424-R529) was used as the immunogen for the IGF2R antibody.

Isotype: IgG2a

Application Details

Application Notes: Optimal dilution of the IGF2R antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the IGF2R antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for IGF2R

Target: IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

Alternative Name: IGF2R

Background: Insulin-like growth factor 2 receptor, also called IGF2R or I-MPR is a protein that in humans is encoded by the IGF2R gene. This gene is mapped to 6q25.3. This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.

UniProt: P11717