PRPF8 antibody (AA 433-2166)

Catalog No. ABIN7874982

The Rabbit Polyclonal anti-PRPF8 antibody is suitable to detect PRPF8 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for PRPF8 antibody (AA 433-2166) (ABIN7874982)

Target: PRPF8 (PRP8 Pre-mRNA Processing Factor 8 (PRPF8))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRPF8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PRPF8 Antibody

Binding Specificity: AA 433-2166

Purpose: PRPF8 Antibody / Pre-mRNA-processing-splicing factor 8

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids E433-H2166) was used as the immunogen for the PRPF8 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PRPF8 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the PRPF8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PRPF8

Target: PRPF8 (PRP8 Pre-mRNA Processing Factor 8 (PRPF8))

Alternative Name: PRPF8

Background: Pre-mRNA-processing-splicing factor 8 is a protein that in humans is encoded by the PRPF8 gene. Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.

UniProt: Q6P2Q9