Mesothelin antibody (AA 44-497)

Catalog No. ABIN7875019

The Rabbit Polyclonal anti-Mesothelin antibody (ABIN7875019) specifically detects Mesothelin in WB and ELISA. The antibody is reactive with Mouse samples.

Quick Overview for Mesothelin antibody (AA 44-497) (ABIN7875019)

Target: Mesothelin (MSLN)

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Mesothelin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Mesothelin Antibody

Binding Specificity: AA 44-497

Purpose: Msln Antibody / Mesothelin

Purification: Antigen affinity purified

Immunogen: An E.coli-derived mouse recombinant protein (Q44-K497) was used as the immunogen for the Msln antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Msln antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Msln antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Mesothelin

Target: Mesothelin (MSLN)

Alternative Name: Msln

Background: Mesothelin, also known as MSLN or MPF, is a protein that in humans is encoded by the MSLN gene. This gene is mapped to 16p13.3. This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas.

UniProt: Q61468

Pathways: EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process