DMRT1 antibody (AA 44-76)

Catalog No. ABIN7875023

This Rabbit Polyclonal antibody specifically detects DMRT1 in IHC (p). It exhibits reactivity toward Zebrafish (Danio rerio).

Quick Overview for DMRT1 antibody (AA 44-76) (ABIN7875023)

Target: DMRT1 (Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DMRT1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DMRT1 Antibody

Binding Specificity: AA 44-76

Purpose: Zebrafish Dmrt1 Antibody / Doublesex and mab 3 related transcription factor 1

Purification: Antigen affinity chromatography

Immunogen: An E.coli-derived zebrafish Dmrt1 recombinant protein (amino acids R44-E76) was used as the immunogen for the Zebrafish Dmrt1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal dilution of the Zebrafish Dmrt1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Zebrafish Dmrt1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for DMRT1

Target: DMRT1 (Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))

Alternative Name: Dmrt1

Background: Doublesex and mab-3 related transcription factor 1, also known as DMRT1, is a protein which in humans is encoded by the DMRT1 gene. This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.

UniProt: Q71MM5