HMOX2 antibody (AA 45-301)

Catalog No. ABIN7875062

This Rabbit Polyclonal antibody specifically detects HMOX2 in WB, ELISA, FACS, IF and IHC (p). It exhibits reactivity toward Human.

Quick Overview for HMOX2 antibody (AA 45-301) (ABIN7875062)

Target: HMOX2 (Heme Oxygenase (Decycling) 2 (HMOX2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMOX2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-HMOX2 Antibody

Binding Specificity: AA 45-301

Purpose: HO-2 Antibody / Heme oxygenase 2 / HMOX2

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids H45-A301) was used as the immunogen for the HO-2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the HO-2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the HO-2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for HMOX2

Target: HMOX2 (Heme Oxygenase (Decycling) 2 (HMOX2))

Alternative Name: HO-2

Background: Heme oxygenase 2 (HMOX2), also known as HO-2, is an enzyme that in humans is encoded by the HMOX2 gene. It is mapped to 16p13.3. HMOX2 belongs to the heme oxygenase family. Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.

UniProt: P30519

Pathways: Transition Metal Ion Homeostasis