PRMT6 antibody (AA 45-348)

Catalog No. ABIN7875068

This Rabbit Polyclonal antibody specifically detects PRMT6 in WB, ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for PRMT6 antibody (AA 45-348) (ABIN7875068)

Target: PRMT6 (Protein Arginine Methyltransferase 6 (PRMT6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRMT6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-PRMT6 Antibody

Binding Specificity: AA 45-348

Purpose: PRMT6 Antibody / Protein arginine N-methyltransferase 6

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids Q45-D348) was used as the immunogen for the PRMT6 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PRMT6 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the PRMT6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PRMT6

Target: PRMT6 (Protein Arginine Methyltransferase 6 (PRMT6))

Alternative Name: PRMT6

Background: Protein arginine N-methyltransferase 6 is an enzyme that in humans is encoded by the PRMT6 gene. The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity.

UniProt: Q96LA8