ACPL2 antibody (AA 45-459)

Catalog No. ABIN7875074

This Rabbit Polyclonal antibody specifically detects ACPL2 in WB, ELISA and FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ACPL2 antibody (AA 45-459) (ABIN7875074)

Target: ACPL2 (Acid Phosphatase-Like 2 (ACPL2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACPL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-ACPL2 Antibody

Binding Specificity: AA 45-459

Purpose: PXYLP1 Antibody / 2-Phosphoxylose phosphatase 1

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (amino acids K45-D459) was used as the immunogen for the PXYLP1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PXYLP1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the PXYLP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ACPL2

Target: ACPL2 (Acid Phosphatase-Like 2 (ACPL2))

Alternative Name: PXYLP1

Background: PXYLP1 dephosphorylates the xylose (xyl) residue in the glycosaminoglycan (GAG)-protein linkage region of proteoglycans, which is required for biosynthetic maturation of the linkage region. Responsible for the 2-O-dephosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature glycosaminoglycan (GAG) chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-O-dephosphorylation during completion of linkage region formation is a prerequisite for the initiation and efficient elongation of the repeating disaccharide region of GAG chains.

UniProt: Q8TE99