Fibronectin antibody (AA 467-595)

Catalog No. ABIN7875148

The Mouse Monoclonal anti-Fibronectin antibody (Clone FN1-2950) (ABIN7875148) specifically detects Fibronectin in ELISA and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Fibronectin antibody (AA 467-595) (ABIN7875148)

Target: Fibronectin

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Fibronectin antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: FN1-2950

Product Details anti-Fibronectin Antibody

Binding Specificity: AA 467-595

Purpose: Fibronectin Antibody

Purification: Protein G affinity chromatography

Immunogen: A portion of amino acids 467-595 from the human protein was used as the immunogen for the Fibronectin antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the Fibronectin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the Fibronectin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Fibronectin

Target: Fibronectin

Background: Fibronectins are disulfide-linked, dimeric glycoproteins of ~440 kDa. They possess at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Epitope of this MAb is located in the 2nd-3rd type-III repeats of fibronectin. Fibronectins are extracellular matrix glycoproteins that are essential for embryonic development. Fibronectins are also involved in cell adhesion, tissue organization, and wound healing. Fibronectins are present in basement membranes, interstitial connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors. This MAb reacts with human cellular fibronectin, but not plasma fibronectin.

UniProt: P02751