CH25H antibody (AA 47-76)

Catalog No. ABIN7875166

The Rabbit Polyclonal anti-CH25H antibody (ABIN7875166) specifically detects CH25H in WB. The antibody is reactive with Human and Mouse samples.

Quick Overview for CH25H antibody (AA 47-76) (ABIN7875166)

Target: CH25H (Cholesterol 25-Hydroxylase (CH25H))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CH25H antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CH25H Antibody

Binding Specificity: AA 47-76

Purpose: CH25H Antibody (N-Terminal Region)

Predicted Reactivity: Pig

Purification: Antigen affinity

Immunogen: A portion of amino acids 47-76 from human CH25H was used as the immunogen for the CH25H antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the CH25H antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CH25H antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CH25H

Target: CH25H (Cholesterol 25-Hydroxylase (CH25H))

Alternative Name: CH25H

Background: Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25- hydroxycholesterol by macrophages may play a role in Leydig cell differentiation. [UniProt]

UniProt: O95992