MAPK8IP1 antibody (AA 470-498)

Catalog No. ABIN7875168

The Rabbit Polyclonal anti-MAPK8IP1 antibody is suitable to detect MAPK8IP1 in samples from Human. It has been validated for WB, IF, IHC (p) and FACS.

Quick Overview for MAPK8IP1 antibody (AA 470-498) (ABIN7875168)

Target: MAPK8IP1 (Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAPK8IP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-MAPK8IP1 Antibody

Binding Specificity: AA 470-498

Purpose: MAPK8IP1 Antibody / JIP1

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 470-498 from the human protein was used as the immunogen for the MAPK8IP1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the MAPK8IP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the MAPK8IP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for MAPK8IP1

Target: MAPK8IP1 (Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1))

Alternative Name: MAPK8IP1

Background: JIP1 is a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2.

UniProt: Q9UQF2