CREB3L1 antibody (AA 481-509)

Catalog No. ABIN7875222

The Rabbit Polyclonal anti-CREB3L1 antibody is suitable to detect CREB3L1 in samples from Human and Mouse. It has been validated for WB, FACS and IHC (p).

Quick Overview for CREB3L1 antibody (AA 481-509) (ABIN7875222)

Target: CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CREB3L1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CREB3L1 Antibody

Binding Specificity: AA 481-509

Purpose: OASIS Antibody / CREB3L1

Purification: Purified

Immunogen: A portion of amino acids 481-509 from the human protein was used as the immunogen for the OASIS antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the OASIS antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the OASIS antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CREB3L1

Target: CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))

Alternative Name: OASIS

Background: CREB3L1 is a transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. It is specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). It may play a role in gliosis. In vitro, it binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE.

UniProt: Q96BA8

Pathways: Thyroid Hormone Synthesis, Chromatin Binding