Myosin Binding Subunit antibody (AA 481-514)
Quick Overview for Myosin Binding Subunit antibody (AA 481-514) (ABIN7875223)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 481-514
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Purpose
- Myosin Phosphatase Antibody / MYPT1 / PPP1R12A
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Purification
- Antigen affinity
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Immunogen
- A portion of amino acids 481-514 from the human MYPT1 was used as the immunogen for the Myosin Phosphatase antibody.
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Isotype
- Ig Fraction
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Application Notes
- The stated application concentrations are suggested starting points. Titration of the Myosin Phosphatase antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the Myosin Phosphatase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Myosin Binding Subunit (MBS)
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Alternative Name
- Myosin Phosphatase
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Background
- Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN- dependent suppression of HIF1A activity. [UniProt]
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UniProt
- O14974
Target
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