Mps1 antibody (AA 487-821)

Catalog No. ABIN7875232

The Rabbit Polyclonal anti-Mps1 antibody (ABIN7875232) specifically detects Mps1 in WB, ELISA, IF, IHC (p) and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Mps1 antibody (AA 487-821) (ABIN7875232)

Target: Mps1 (TTK)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Mps1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-Mps1 Antibody

Binding Specificity: AA 487-821

Purpose: TTK Antibody

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids Q487-S821) was used as the immunogen for the TTK antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the TTK antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the TTK antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Mps1

Target: Mps1 (TTK)

Alternative Name: TTK

Background: Dual specificity protein kinase TTK is a protein that in humans is encoded by the TTK gene. This gene is mapped to 6q14.1. This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.

UniProt: P33981