ALDOA antibody (AA 50-364)

Catalog No. ABIN7875404

This Mouse Monoclonal antibody specifically detects ALDOA in WB, IF, FACS and IHC (p). It exhibits reactivity toward Human.

Quick Overview for ALDOA antibody (AA 50-364) (ABIN7875404)

Target: ALDOA (Aldolase A, Fructose-Bisphosphate (ALDOA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ALDOA antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 6H8

Product Details anti-ALDOA Antibody

Binding Specificity: AA 50-364

Purpose: ALDOA Antibody / Aldolase A

Purification: Affinity purified

Immunogen: A human recombinant partial protein (amino acids E50-Y364) was used as the immunogen for the ALDOA antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the ALDOA antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ALDOA antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ALDOA

Target: ALDOA (Aldolase A, Fructose-Bisphosphate (ALDOA))

Alternative Name: ALDOA

Background: Aldolase A (ALDOA, or ALDA), also known as fructose-bisphosphate aldolase, is an enzyme that in humans is encoded by the ALDOA gene on chromosome 16. This gene encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10.

UniProt: P04075

Pathways: Ribonucleoside Biosynthetic Process