Neuropilin 1 antibody (AA 504-827)

Catalog No. ABIN7875497

This Mouse Monoclonal antibody specifically detects Neuropilin 1 in WB, FACS and IF. It exhibits reactivity toward Human and Rat.

Quick Overview for Neuropilin 1 antibody (AA 504-827) (ABIN7875497)

Target: Neuropilin 1 (NRP1)

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Neuropilin 1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: 8G6G7

Product Details anti-Neuropilin 1 Antibody

Binding Specificity: AA 504-827

Purpose: NRP1 Antibody / Neuropilin 1

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids K504-T827) was used as the immunogen for the NRP1 antibody.

Isotype: IgG2a

Application Details

Application Notes: Optimal dilution of the NRP1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the NRP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Neuropilin 1

Target: Neuropilin 1 (NRP1)

Alternative Name: NRP1

Background: This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contain a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors, they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

UniProt: O14786

Pathways: Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals