VAV3 antibody (AA 507-702)

Catalog No. ABIN7875501

The Rabbit Polyclonal anti-VAV3 antibody is suitable to detect VAV3 in samples from Human. It has been validated for WB, ELISA and IF.

Quick Overview for VAV3 antibody (AA 507-702) (ABIN7875501)

Target: VAV3 (Vav 3 Oncogene (VAV3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VAV3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-VAV3 Antibody

Binding Specificity: AA 507-702

Purpose: VAV3 Antibody

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids D507-E702) was used as the immunogen for the VAV3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the VAV3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the VAV3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for VAV3

Target: VAV3 (Vav 3 Oncogene (VAV3))

Alternative Name: VAV3

Background: Guanine nucleotide exchange factor VAV3 is a protein that in humans is encoded by the VAV3 gene. This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

UniProt: Q9UKW4

Pathways: Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway