PRP19 antibody (AA 51-359)

Catalog No. ABIN7875518

This Rabbit Polyclonal antibody specifically detects PRP19 in WB, ELISA, IF and FACS. It exhibits reactivity toward Human.

Quick Overview for PRP19 antibody (AA 51-359) (ABIN7875518)

Target: PRP19 (PRPF19) (Pre-mRNA Processing Factor 19 (PRPF19))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRP19 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-PRP19 Antibody

Binding Specificity: AA 51-359

Purpose: SNEV Antibody / PRP19 / NMP200

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids Q51-H359) was used as the immunogen for the SNEV antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the SNEV antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the SNEV antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PRP19

Target: PRP19 (PRPF19) (Pre-mRNA Processing Factor 19 (PRPF19))

Alternative Name: SNEV

Background: Pre-mRNA-processing factor 19, also called PRP19, SNEV (Senescence evasion factor) and NMP200 (Nuclear matrix protein 200), is a protein that in humans is encoded by the PRPF19 gene. Enables identical protein binding activity and ubiquitin-ubiquitin ligase activity. Involved in several processes, including DNA damage checkpoint signaling, cellular protein metabolic process, and mRNA splicing, via spliceosome. Acts upstream of or within protein polyubiquitination. Located in cytoplasm, nuclear speck, and site of double-strand break. Part of Prp19 complex and U2-type catalytic step 2 spliceosome. Colocalizes with DNA replication factor A complex.

UniProt: Q9UMS4

Pathways: Ribonucleoprotein Complex Subunit Organization