Dysferlin antibody (AA 51-747)

Catalog No. ABIN7875526

The Rabbit Polyclonal anti-Dysferlin antibody (ABIN7875526) specifically detects Dysferlin in WB, ELISA, IF, FACS and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Dysferlin antibody (AA 51-747) (ABIN7875526)

Target: Dysferlin (DYSF)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dysferlin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Dysferlin Antibody

Binding Specificity: AA 51-747

Purpose: DYSF Antibody / Dysferlin

Purification: Affinity purified

Immunogen: An E. coli-derived human protein (amino acids E51-H747) was used as the immunogen for the DYSF antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the DYSF antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the DYSF antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Dysferlin

Target: Dysferlin (DYSF)

Alternative Name: DYSF

Background: Dysferlin also known as dystrophy-associated fer-1-like protein is a protein that in humans is encoded by the DYSF gene. The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by this gene binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy. Alternative splicing results in multiple transcript variants.

UniProt: O75923