ITSN1 antibody (AA 522-1721)

Catalog No. ABIN7875583

The Rabbit Polyclonal anti-ITSN1 antibody (ABIN7875583) specifically detects ITSN1 in WB, ELISA, FACS, IF and IHC (p). The antibody is reactive with Human samples.

Quick Overview for ITSN1 antibody (AA 522-1721) (ABIN7875583)

Target: ITSN1 (Intersectin 1 (ITSN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITSN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ITSN1 Antibody

Binding Specificity: AA 522-1721

Purpose: Intersectin 1 Antibody / ITSN1

Purification: Antigen affinity chromatography

Immunogen: An E.coli-derived human recombinant protein (amino acids A522-P1721) was used as the immunogen for the Intersectin 1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Intersectin 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Intersectin 1 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ITSN1

Target: ITSN1 (Intersectin 1 (ITSN1))

Alternative Name: Intersectin 1

Background: Intersectin-1 is a protein that, in humans, is encoded by the ITSN1 gene. The protein encoded by this gene is a cytoplasmic membrane-associated protein that indirectly coordinates endocytic membrane traffic with the actin assembly machinery. In addition, the encoded protein may regulate the formation of clathrin-coated vesicles and could be involved in synaptic vesicle recycling. This protein has been shown to interact with dynamin, CDC42, SNAP23, SNAP25, SPIN90, EPS15, EPN1, EPN2, and STN2. Multiple transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been characterized so far.

UniProt: Q15811

Pathways: Neurotrophin Signaling Pathway