BCL6 antibody (AA 528-601)

Catalog No. ABIN7875587

This Mouse Monoclonal antibody specifically detects BCL6 in FACS. It exhibits reactivity toward Human.

Quick Overview for BCL6 antibody (AA 528-601) (ABIN7875587)

Target: BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BCL6 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Grade: Carrier-free

Clone: PCRP-BCL6-1B1

Product Details anti-BCL6 Antibody

Binding Specificity: AA 528-601

Purpose: BCL6 Antibody / B-Cell Lymphoma 6 Protein (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 528-601) from the human protein was used as the immunogen for the BCL6 antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the BCL6 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the BCL6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for BCL6

Target: BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

Alternative Name: BCL6

Background: Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL).The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ( L&H ) cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.

UniProt: P41182

Pathways: Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus