BCL6 antibody (AA 501-600)

Catalog No. ABIN749843

There are 2+ publications for this product available. The Rabbit Polyclonal anti-BCL6 antibody is suitable to detect BCL6 in samples from Human. It has been validated for WB, IF, IHC (p) and IHC (fro).

Quick Overview for BCL6 antibody (AA 501-600) (ABIN749843)

Target: BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL6 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-BCL6 Antibody

Binding Specificity: AA 501-600

Purpose: Bcl-6 Polyclonal Antibody

Cross-Reactivity: Human, Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Bcl-6

Isotype: IgG

Application Details

Application Notes: WB(1:500-1000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-BCL6 antibody (ABIN749843)

Szabó, Gáspár, Dajnoki, Papp, Fábos, Szegedi, Zeher: "Expansion of circulating follicular T helper cells associates with disease severity in childhood atopic dermatitis." in: Immunology letters, Vol. 189, pp. 101-108, (2017) (PubMed).

Gong, Zhu, Pang, Ai, Gong, La, Ding: "Increased levels of CCR7(lo)PD-1(hi) CXCR5+ CD4+ T cells, and associated factors Bcl-6, CXCR5, IL-21 and IL-6 contribute to repeated implantation failure." in: Experimental and therapeutic medicine, Vol. 14, Issue 6, pp. 5931-5941, (2017) (PubMed).

Target Details for BCL6

Target: BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

Alternative Name: Bcl6

Background: Synonyms: Bcl-6/5, Bcl-6+Bcl-5, B-cell lymphoma 6 protein isoform 1, zinc finger transcription factor BCL6S, B-cell lymphoma 6 protein transcript, BCL-5, BCL6, Bcl 6, protein LAZ-3, B-cell lymphoma 5 protein, zinc finger and BTB domain-containing protein 27, lymphoma-associated zinc finger gene on chromosome 3, zinc finger protein 51, cys-his2 zinc finger transcription factor, BCL5, BCL6A, LAZ3, ZBTB27, ZNF51, BCL6_HUMAN.

Gene ID: 604

UniProt: P41182

Pathways: Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus