GIT1 antibody (AA 533-561)
Quick Overview for GIT1 antibody (AA 533-561) (ABIN7875607)
Target
See all GIT1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 533-561
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Purpose
- GIT1 Antibody / p95-APP1
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Purification
- Antigen affinity purified
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Immunogen
- A portion of amino acids 533-561 from the human protein was used as the immunogen for the GIT1 antibody.
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Isotype
- Ig Fraction
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Application Notes
- The stated application concentrations are suggested starting points. Titration of the GIT1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the GIT1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- GIT1
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Alternative Name
- GIT1
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Background
- GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes (from SwissProt).
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UniProt
- Q9Y2X7
Target
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