RNF216 antibody (AA 538-813)

Catalog No. ABIN7875630

The Rabbit Polyclonal anti-RNF216 antibody is suitable to detect RNF216 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and FACS.

Quick Overview for RNF216 antibody (AA 538-813) (ABIN7875630)

Target: RNF216 (Ring Finger Protein 216 (RNF216))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF216 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-RNF216 Antibody

Binding Specificity: AA 538-813

Purpose: RNF216 Antibody / TRIAD3

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids K538-R813) was used as the immunogen for the RNF216 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the RNF216 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the RNF216 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for RNF216

Target: RNF216 (Ring Finger Protein 216 (RNF216))

Alternative Name: RNF216

Background: E3 ubiquitin-protein ligase RNF216 is an enzyme that in humans is encoded by the RNF216 gene. This gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Several alternatively spliced transcript variants have been described for this locus but the full-length natures of only some are known.

UniProt: Q9NWF9