SERPINA7 antibody (AA 55-389)

Catalog No. ABIN7875690

The Rabbit Polyclonal anti-SERPINA7 antibody is suitable to detect SERPINA7 in samples from Human. It has been validated for WB, ELISA, FACS and IHC (p).

Quick Overview for SERPINA7 antibody (AA 55-389) (ABIN7875690)

Target: SERPINA7 (Serpin Family A Member 7 (SERPINA7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINA7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SERPINA7 Antibody

Binding Specificity: AA 55-389

Purpose: Thyroxine Binding Globulin Antibody / TBG / SERPINA7

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids R55-R389) was used as the immunogen for the Thyroxine Binding Globulin antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Thyroxine Binding Globulin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Thyroxine Binding Globulin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SERPINA7

Target: SERPINA7 (Serpin Family A Member 7 (SERPINA7))

Alternative Name: Thyroxine Binding Globulin

Background: Thyroxine-binding globulin (TBG) is a globulin protein that in humans is encoded by the SERPINA7 gene. There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.

UniProt: P05543

Pathways: Hormone Transport