CEA antibody (AA 553-678)
Quick Overview for CEA antibody (AA 553-678) (ABIN7875714)
Target
See all CEA AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 553-678
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Purpose
- Carcinoembryonic Antigen Antibody / CEA
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Purification
- Antigen affinity purified
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Immunogen
- E. coli-derived recombinant human protein (amino acids N553-G678) was used as the immunogen for the Carcinoembryonic Antigen antibody.
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Isotype
- IgG
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Application Notes
- Optimal dilution of the Carcinoembryonic Antigen antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Storage
- 4 °C,-20 °C
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Storage Comment
- After reconstitution, the Carcinoembryonic Antigen antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- CEA (Carcinoembryonic Antigen Gene Family (CEA))
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Alternative Name
- Carcinoembryonic Antigen
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Background
- CEA (Carcinoembryonic antigen) is a glycoprotein involved in cell adhesion. It is normally produced during fetal development, but the production of CEA stops before birth. Therefore, it is not usually present in the blood of healthy adults, although levels are raised in heavy smokers. CEA is a glycosyl phosphatidyl inositol(GPI)-cell surface anchored glycoprotein whose specialized sialofucosylated glycoforms serve as functional colon carcinoma L-selectin and E-selectin ligands, which may be critical to the metastatic dissemination of colon carcinoma cells. CEA and related genes make up the CEA family belonging to the immunoglobulin superfamily. In humans, the carcinoembryonic antigen family consists of 29 genes, 18 of which are normally expressed.
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UniProt
- P06731
Target
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