DDX1 antibody (AA 562-740)

Catalog No. ABIN7875786

The Rabbit Polyclonal anti-DDX1 antibody is suitable to detect DDX1 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IF, IP, FACS and IHC (p).

Quick Overview for DDX1 antibody (AA 562-740) (ABIN7875786)

Target: DDX1 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 1 (DDX1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DDX1 Antibody

Binding Specificity: AA 562-740

Purpose: DEAD box protein 1 Antibody / DDX1

Purification: Affinity purified

Immunogen: A human recombinant partial protein (amino acids K562-F740) was used as the immunogen for the DEAD box protein 1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the DEAD box protein 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the DEAD box protein 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for DDX1

Target: DDX1 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 1 (DDX1))

Alternative Name: DEAD box protein 1

Background: DEAD box protein 1 (DDX1) is a member of the DEAD-box RNA helicase family, a group of proteins defined by the conserved Asp-Glu-Ala-Asp (DEAD) motif. These proteins participate in a wide variety of cellular processes involving RNA metabolism, including transcription, splicing, mRNA transport, and ribosome biogenesis. DEAD box protein 1 functions as an ATP-dependent RNA helicase, unwinding RNA secondary structures to facilitate proper RNA processing. Researchers often employ a DEAD box protein 1 antibody to study these fundamental processes in molecular and cellular biology.

In addition to its role in RNA metabolism, DEAD box protein 1 has been implicated in maintaining genomic stability. It interacts with DNA repair proteins and contributes to the repair of double-strand breaks, suggesting it acts at the interface between RNA regulation and DNA integrity. By using a DEAD box protein 1 antibody, researchers can explore its functions in cellular stress responses, DNA repair pathways, and cell cycle progression.

Elevated expression of DEAD box protein 1 has been observed in various cancers, linking it to tumor biology and uncontrolled cell proliferation. It has also been connected to viral replication, where it interacts with viral RNA to promote or regulate infection. These diverse roles make it a protein of interest in oncology, virology, and RNA biology. Employing a DEAD box protein 1 antibody provides valuable insights into its activity across multiple biological contexts.

NSJ Bioreagents provides a high-quality DEAD box protein 1 antibody validated for applications including western blot, immunohistochemistry, and immunoprecipitation. Choosing a reliable DEAD box protein 1 antibody ensures accurate and reproducible detection in studies of RNA helicases, genomic stability, and disease mechanisms.

UniProt: Q92499

Pathways: Ribonucleoprotein Complex Subunit Organization