Septin 9 antibody (AA 57-85)

Catalog No. ABIN7875816

The Rabbit Polyclonal anti-Septin 9 antibody is suitable to detect Septin 9 in samples from Human. It has been validated for WB, FACS and IHC (p).

Quick Overview for Septin 9 antibody (AA 57-85) (ABIN7875816)

Target: Septin 9 (SEPT9)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Septin 9 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Septin 9 Antibody

Binding Specificity: AA 57-85

Purpose: Septin 9 Antibody / SEPT9

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 57-85 from the human protein were used as the immunogen for the Septin 9 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Septin 9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Septin 9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Septin 9

Target: Septin 9 (SEPT9)

Alternative Name: Septin 9

Background: The maf oncogene was identified by structural analysis of the AS42 avian transforming retrovirus genome. The Maf family is divided into two subclasses, large Mafs (vMaf, cMaf, MafB and Nrl) and small Mafs (MafF, MafK, and MafG). Both subclasses contain leucinezipper motifs, which allow homodimerization as well as heterodimerization with a variety of other bZip transcription factors. Large Mafs also contain an acidic transactivation domain absent in the small Maf proteins. Although they do not possess inherent transactivation activity, small Maf proteins can act as positive regulators of transcription by targeting transcriptionally active dimerization partners to specific DNA regulatory elements. Conversely, small Mafs can act also as negative regulators of transcription by recruiting transcriptional repressors or by forming homodimers that can replace active dimers. Human MafF was isolated in a yeast one-hybrid system from a human myometrium cDNA library. Human MAFF encodes a 164 amino acids proten. Like other small MAFF proteins, it contains an extended leucine zipper structure and lacks an N-terminal transactivating domain. The three small Maf proteins have been implicated in a number of physiological processes, including development, differentiation, haematopoiesis and stress response. Interestingly, these three proteins regulate the stress response via different mechanisms.

UniProt: Q9UHD8