MAGE-Like 2 antibody (AA 578-847)

Catalog No. ABIN7875833

This Rabbit Polyclonal antibody specifically detects MAGE-Like 2 in ELISA, WB, IHC (p) and FACS. It exhibits reactivity toward Human.

Quick Overview for MAGE-Like 2 antibody (AA 578-847) (ABIN7875833)

Target: MAGE-Like 2 (MAGEL2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGE-Like 2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-MAGE-Like 2 Antibody

Binding Specificity: AA 578-847

Purpose: MAGEL2 Antibody / MAGE-like protein 2

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (amino acids Q578-A847) was used as the immunogen for the MAGEL2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the MAGEL2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the MAGEL2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for MAGE-Like 2

Target: MAGE-Like 2 (MAGEL2)

Alternative Name: MAGEL2

Background: Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS.

UniProt: Q9UJ55