GRAF antibody (AA 584-791)

Catalog No. ABIN7875870

The Rabbit Polyclonal anti-GRAF antibody is suitable to detect GRAF in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for GRAF antibody (AA 584-791) (ABIN7875870)

Target: GRAF (ARHGAP26) (rho GTPase Activating Protein 26 (ARHGAP26))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRAF antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GRAF Antibody

Binding Specificity: AA 584-791

Purpose: ARHGAP26 Antibody / GRAF

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids S584-E791) was used as the immunogen for the ARHGAP26 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ARHGAP26 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ARHGAP26 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for GRAF

Target: GRAF (ARHGAP26) (rho GTPase Activating Protein 26 (ARHGAP26))

Alternative Name: ARHGAP26

Background: Rho GTPase activating protein 26 (ARHGAP26) also known as GTPase Regulator Associated with Focal Adhesion Kinase (GRAF) is a protein that in humans is encoded by the ARHGAP26 gene. Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: Q9UNA1