PRSS8 antibody (AA 59-322)

Catalog No. ABIN7875900

The Rabbit Polyclonal anti-PRSS8 antibody is suitable to detect PRSS8 in samples from Human. It has been validated for WB, ELISA and FACS.

Quick Overview for PRSS8 antibody (AA 59-322) (ABIN7875900)

Target: PRSS8 (Protease, serine, 8 (PRSS8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRSS8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-PRSS8 Antibody

Binding Specificity: AA 59-322

Purpose: Prostasin Antibody / PRSS8

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids Q59-R322) was used as the immunogen for the Prostasin antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Prostasin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Prostasin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PRSS8

Target: PRSS8 (Protease, serine, 8 (PRSS8))

Alternative Name: Prostasin

Background: Prostasin is a protein that in humans is encoded by the PRSS8 gene This gene encodes a member of the peptidase S1 or chymotrypsin family of serine proteases. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate via a disulfide bond to form the heterodimeric enzyme. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. This protease exhibits trypsin-like substrate specificity, cleaving protein substrates at the carboxyl terminus of lysine or arginine residues. The encoded protease partially mediates proteolytic activation of the epithelial sodium channel, a regulator of sodium balance, and may also play a role in epithelial barrier formation.

UniProt: Q16651