The Rabbit Polyclonal anti-SERINC3 antibody (ABIN7875904) specifically detects SERINC3 in WB, ELISA, IF and FACS.
The antibody is reactive with Mouse and Rat samples.
SERINC3
Reactivity: Human
WB, ELISA
Host: Rabbit
Polyclonal
PE
Application Notes
Optimal dilution of the Aigp1 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Storage
4 °C,-20 °C
Storage Comment
After reconstitution, the Aigp1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Target
SERINC3
(Serine Incorporator 3 (SERINC3))
Alternative Name
Aigp1
Background
Serine incorporator 3 / Axotomy-induced glycoprotein 1 is a protein that in humans is encoded by the SERINC3 gene. Also found on the membranes of the Golgi apparatus within cells, Axotomy-induced glycoprotein 1 is highly expressed in neuronal populations but is also found in thymus, kidney, liver and testis. Expression levels in tumors can be as much as tenfold the amount found in normal tissue of the same type. This increased expression implicates Axotomy-induced glycoprotein 1 as being involved in the cellular transformation from normal to malignant tissue. It is believed it contributes to oncogenesis by partially protecting cells from serum starvation and etoposide-induced apoptosis.