SSB antibody (AA 6-283)

Catalog No. ABIN7875950

This Rabbit Polyclonal antibody specifically detects SSB in WB, ELISA, IF, IHC (p) and FACS. It exhibits reactivity toward Human.

Quick Overview for SSB antibody (AA 6-283) (ABIN7875950)

Target: SSB (Sjogren Syndrome Antigen B (SSB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-SSB Antibody

Binding Specificity: AA 6-283

Purpose: SSB Antibody / Sjoegren syndrome type B antigen / Lupus La protein

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids D6-L283) was used as the immunogen for the SSB antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the SSB antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the SSB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SSB

Target: SSB (Sjogren Syndrome Antigen B (SSB))

Alternative Name: SSB

Background: Sjogren syndrome type B antigen (SS-B) also known as Lupus La protein is a protein that in humans is encoded by the SSB gene. The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein.

UniProt: P05455