ALDH1A1 antibody (AA 6-342)

Catalog No. ABIN7875955

The Mouse Monoclonal anti-ALDH1A1 antibody (Clone 4C3) (ABIN7875955) specifically detects ALDH1A1 in WB, IF, FACS and IHC (p). The antibody is reactive with Human samples.

Quick Overview for ALDH1A1 antibody (AA 6-342) (ABIN7875955)

Target: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ALDH1A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 4C3

Product Details anti-ALDH1A1 Antibody

Binding Specificity: AA 6-342

Purpose: Aldehyde Dehydrogenase 1A1 Antibody / ALDH1A1

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids T6-Q342) was used as the immunogen for the Aldehyde Dehydrogenase 1A1 antibody.

Isotype: IgG2a

Application Details

Application Notes: Optimal dilution of the Aldehyde Dehydrogenase 1A1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Aldehyde Dehydrogenase 1A1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ALDH1A1

Target: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Alternative Name: Aldehyde Dehydrogenase 1A1

Background: Aldehyde dehydrogenase 1 family, member A1, also known as ALDH1A1 or retinaldehyde dehydrogenase 1 (RALDH1), is an enzyme that in humans is encoded by the ALDH1A1 gene. It is mapped to 9q21.13. The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet.

UniProt: P00352

Pathways: Dopaminergic Neurogenesis