RNF8 antibody (AA 61-485)

Catalog No. ABIN7876109

This Rabbit Polyclonal antibody specifically detects RNF8 in WB, ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for RNF8 antibody (AA 61-485) (ABIN7876109)

Target: RNF8 (Ring Finger Protein 8 (RNF8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-RNF8 Antibody

Binding Specificity: AA 61-485

Purpose: RNF8 Antibody

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids R61-F485) was used as the immunogen for the RNF8 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the RNF8 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the RNF8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for RNF8

Target: RNF8 (Ring Finger Protein 8 (RNF8))

Alternative Name: RNF8

Background: E3 ubiquitin-protein ligase RNF8 is an enzyme that in humans is encoded by the RNF8 gene. The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants.

UniProt: O76064

Pathways: Production of Molecular Mediator of Immune Response