Claudin 2 antibody (AA 63-230)

Catalog No. ABIN7876234

The Rabbit Polyclonal anti-Claudin 2 antibody (ABIN7876234) specifically detects Claudin 2 in WB, ELISA, FACS and IF. The antibody is reactive with Human samples.

Quick Overview for Claudin 2 antibody (AA 63-230) (ABIN7876234)

Target: Claudin 2 (CLDN2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Product Details anti-Claudin 2 Antibody

Binding Specificity: AA 63-230

Purpose: Claudin 2 Antibody / CLDN2

Purification: Affinity purified

Immunogen: An E. coli-derived human protein (amino acids Q63-V230) was used as the immunogen for the Claudin 2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Claudin 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Claudin 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Claudin 2

Target: Claudin 2 (CLDN2)

Alternative Name: Claudin 2

Background: Claudin-2 is a protein that in humans is encoded by the CLDN2 gene. By genomic sequence analysis, this gene is mapped to chromosome Xq22.3-q23. This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. By expression in a human intestinal epithelial cell line, it was determined that the intestine-specific homeodomain proteins CDX1 and CDX2 activated a reporter plasmid driven by the CLDN2 promoter.

UniProt: P57739

Pathways: Hepatitis C