HMGB2 antibody (AA 64-97)

Catalog No. ABIN7876263

The Rabbit Polyclonal anti-HMGB2 antibody is suitable to detect HMGB2 in samples from Zebrafish (Danio rerio). It has been validated for WB and IHC (p).

Quick Overview for HMGB2 antibody (AA 64-97) (ABIN7876263)

Target: HMGB2 (High Mobility Group Box 2 (HMGB2))

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGB2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-HMGB2 Antibody

Binding Specificity: AA 64-97

Purpose: Zebrafish Hmgb2 Antibody / Hmgb2a / Hmgb2b

Purification: Antigen affinity chromatography

Immunogen: An E.coli-derived zebrafish Hmgb2a/b recombinant protein (amino acids K64-R97) was used as the immunogen for the Zebrafish Hmgb2 antibody. This antibody will detect the a and b isoforms.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal dilution of the Zebrafish Hmgb2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Zebrafish Hmgb2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for HMGB2

Target: HMGB2 (High Mobility Group Box 2 (HMGB2))

Alternative Name: Hmgb2

Background: High-mobility group protein B2, also known as high-mobility group protein 2 (HMG-2), is a protein that in humans is encoded by the HMGB2 gene. This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.

UniProt: Q32PT3

Pathways: Cellular Response to Molecule of Bacterial Origin