HSPH1 antibody (AA 653-858)

Catalog No. ABIN7876321

The Mouse Monoclonal anti-HSPH1 antibody (Clone 3D10) (ABIN7876321) specifically detects HSPH1 in WB, IF, IHC (p) and FACS. The antibody is reactive with Human samples.

Quick Overview for HSPH1 antibody (AA 653-858) (ABIN7876321)

Target: HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HSPH1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: 3D10

Product Details anti-HSPH1 Antibody

Binding Specificity: AA 653-858

Purpose: Hsp105 Antibody

Purification: Affinity purified

Immunogen: A human recombinant protein (amino acids Y653-D858) was used as the immunogen for the Hsp105 antibody.

Isotype: IgG1

Application Details

Application Notes: Optimal dilution of the Hsp105 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Hsp105 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for HSPH1

Target: HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

Alternative Name: Hsp105

Background: HSP105 (HEAT-SHOCK 105/110-KD PROTEIN 1), also called HSPH1 or HSP110, is a protein that in humans is encoded by the HSPH1 gene. Immunohistochemical analysis localizes HSP105 mainly in the cytoplasm. Database analysis indicates that both HSP105 isoforms are highly conserved during evolution. By analysis of radiation hybrids and human/rodent hybrid cell lines, the HSPH1 gene is mapped to chromosome 13. Both HSP105-alpha and HSP105-beta are upregulated in HeLa cells exposed to heat shock. HSP105-alpha, but not HSP105-beta, is also upregulate in response to other cell stresses. Following heat shock, HSP105 relocalizes from a cytoplasmic to perinuclear position. Besides, HSP110 may thus constitute a major determinant for both prognosis and treatment response in colorectal cancer.

UniProt: Q92598