PLOD1 antibody (AA 66-94)

Catalog No. ABIN7876355

This Rabbit Polyclonal antibody specifically detects PLOD1 in WB, FACS and IHC (p). It exhibits reactivity toward Human.

Quick Overview for PLOD1 antibody (AA 66-94) (ABIN7876355)

Target: PLOD1 (Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLOD1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PLOD1 Antibody

Binding Specificity: AA 66-94

Purpose: LH1 Antibody / PLOD1

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 66-94 from the human protein were used as the immunogen for the LH1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the LH1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the LH1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for PLOD1

Target: PLOD1 (Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1))

Alternative Name: LH1

Background: Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity.

UniProt: Q02809