UVRAG antibody (AA 666-699)

Catalog No. ABIN7876363

The Rabbit Polyclonal anti-UVRAG antibody (ABIN7876363) specifically detects UVRAG in WB, IF and IHC (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for UVRAG antibody (AA 666-699) (ABIN7876363)

Target: UVRAG (UV Radiation Resistance Associated Gene (UVRAG))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UVRAG antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-UVRAG Antibody

Binding Specificity: AA 666-699

Purpose: UVRAG Antibody

Purification: Purified

Immunogen: A portion of amino acids 666-699 from the human protein was used as the immunogen for the UVRAG antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the UVRAG antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the UVRAG antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for UVRAG

Target: UVRAG (UV Radiation Resistance Associated Gene (UVRAG))

Alternative Name: UVRAG

Background: UVRAG complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.

UniProt: Q9P2Y5