LZIC antibody (AA 67-187)

Catalog No. ABIN7876370

This Rabbit Polyclonal antibody specifically detects LZIC in IHC (p). It exhibits reactivity toward Zebrafish (Danio rerio).

Quick Overview for LZIC antibody (AA 67-187) (ABIN7876370)

Target: LZIC (Leucine Zipper and CTNNBIP1 Domain Containing (LZIC))

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LZIC antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-LZIC Antibody

Binding Specificity: AA 67-187

Purpose: Zebrafish Lzic Antibody / Leucine zipper and ICAT homologous domain-containing protein

Purification: Antigen affinity chromatography

Immunogen: An E.coli-derived zebrafish Lzic recombinant protein (amino acids N67-K187) was used as the immunogen for the Zebrafish Lzic antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal dilution of the Zebrafish Lzic antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Zebrafish Lzic antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for LZIC

Target: LZIC (Leucine Zipper and CTNNBIP1 Domain Containing (LZIC))

Alternative Name: Lzic

Background: LZIC is closely related to ICAT, a physiological inhibitor of the Wnt pathway that interacts physically and functionally with beta-catenin to prevent the transcription of Wnt target genes. LZIC's ICAT-homologous region is highly similar to ICAT with particular conservation of residues that are used by ICAT for beta-catenin-binding. LZIC does not interact with beta-catenin in vitro or in vivo. LZIC is a protein conserved in vertebrates, is required for neuronal survival.

UniProt: Q6DHH7