LZIC antibody (AA 67-187)

Catalog No. ABIN7876371

The Rabbit Polyclonal anti-LZIC antibody is suitable to detect LZIC in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IF, IHC (p), FACS and IP.

Quick Overview for LZIC antibody (AA 67-187) (ABIN7876371)

Target: LZIC (Leucine Zipper and CTNNBIP1 Domain Containing (LZIC))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LZIC antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunoprecipitation (IP)

Product Details anti-LZIC Antibody

Binding Specificity: AA 67-187

Purpose: LZIC Antibody / Leucine zipper and ICAT homologous domain-containing protein

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (amino acids N67-K187) was used as the immunogen for the LZIC antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the LZIC antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the LZIC antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for LZIC

Target: LZIC (Leucine Zipper and CTNNBIP1 Domain Containing (LZIC))

Alternative Name: LZIC

Background: LZIC is closely related to ICAT, a physiological inhibitor of the Wnt pathway that interacts physically and functionally with b-catenin to prevent the transcription of Wnt target genes. LZIC's ICAT-homologous region is highly similar to ICAT with particular conservation of residues that are used by ICAT for b-catenin binding. LZIC does not interact with b-catenin in vitro or in vivo. LZIC is a protein conserved in vertebrates, is required for neuronal survival.

UniProt: Q8WZA0