PAICS antibody (AA 69-425)

Catalog No. ABIN7876446

The Rabbit Polyclonal anti-PAICS antibody is suitable to detect PAICS in samples from Human. It has been validated for WB, ELISA and FACS.

Quick Overview for PAICS antibody (AA 69-425) (ABIN7876446)

Target: PAICS (phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAICS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-PAICS Antibody

Binding Specificity: AA 69-425

Purpose: PAICS Antibody / AIRC / ADE2

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (amino acids Q69-L425) was used as the immunogen for the PAICS antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PAICS antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the PAICS antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PAICS

Target: PAICS (phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS))

Alternative Name: PAICS

Background: This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: P22234

Pathways: Chromatin Binding